South Dakota Cannabis Compliance & Licensing

Informational summary of public regulatory information — not legal advice. Confirm current requirements with the state regulator before acting.

South Dakota voters approved both medical (Measure 26) and adult-use (Amendment A) cannabis in 2020, but the state Supreme Court invalidated the adult-use amendment in 2021 on single-subject grounds. The medical program, run by the Department of Health, began state-licensed sales in 2022, alongside tribal cannabis operations launched earlier under tribal sovereignty. Subsequent adult-use ballot attempts failed in 2022 and 2024. Ancillary firms should plan around a small, medical-only market with active tribal participation.

Market & regulatory snapshot

License dataThis state's registry ships in an upcoming coverage wave — claim your listing to be notified when it lands.
Legal sinceMedical only: 2020 (Measure 26); sales 2022
Primary regulatorSouth Dakota Department of Health, Medical Cannabis Program
Source: state regulator · as of 2026-01
Legal statusMedical only: 2020 (Measure 26); sales 2022
Source: state statute · as of 2026-01
Track-and-trace systemMetrc
Source: South Dakota Department of Health, Medical Cannabis Program · as of 2026-01

Frequently asked questions

Is recreational marijuana legal in South Dakota?
No. Voters approved adult-use in 2020, but the state Supreme Court struck it down in 2021; the medical program (Measure 26) survived and has operated since 2022, while later adult-use measures failed in 2022 and 2024.